Qualifications and Career

Commissions of Trust

Academic Distinctions

Selected Publications (last 10 years)

Fricke AL, Mühlhäuser WD, Reimann L, …, Warscheid B (2023) Phosphoproteomics profiling defines a target landscape of the basophilic protein kinases AKT, S6K and RSK in skeletal myotubes; J Proteome Res 22 :768-789.

Dewar C, Oeljeklaus S, Mani J, …, Warscheid B*, Schneider A* (2022) Mistargeting of aggregation prone mitochondrial proteins activates a nucleus-mediated posttranscriptional quality control pathway in trypanosomes. Nat Commun 13: 3084. *senior authorship

Morgenstern M, Peikert CD, Lübbert P, …, Warscheid B (2021) Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Cell Metab 33: 2464-2483.

Schwarz J, Grundmann L, Kokot T, …, Warscheid B (2021) Quantitative proteomics identifies PTP1B as modulator of B cell antigen receptor signaling, Life Sci Alliance, 4: e202101084.

Dannenmeier S, Desroches Altamirano C, …, Warscheid B (2021) Quantitative proteomics identifies Ola1p as a positive regulator of heat shock response, J Biol Chem, 297:101050.

Reimann L, Schwäble AN, Fricke A, …, Warscheid B (2020) Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C. Commun Biol 3:253.

Lill P, Hansen T, Wendscheck D, …, Warscheid B*, Erdmann R*, Gatsogiannis C* (2020) Towards the molecular architecture of the peroxisomal receptor docking complex; Proc Natl Acad Sci U S A, 117(52):33216-33224. *senior authorship

Mårtensson CU, Priesnitz C, Song, …, Warscheid, B., Becker, T. (2019) Mitochondrial protein translocation associated degradation, Nature, 569:679-683.

Topf U, Suppanz I, Samluk L, …, Warscheid B (2018) Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species. Nat Commun 9: 324.

Dannenmaier S, Stiller S, Morgenstern M, ..., Warscheid B. (2018) Complete native stable isotope labeling by amino acids of Saccharomyces cerevisiae for global proteomic analysis, Anal Chem, 90:10501-10509.

Morgenstern M, Stiller SB, Lübbert P, …, Warscheid B (2017) Definition of a high confidence  me at quantitative scale. Cell Rep 9: 2836-2852.

Peikert CD, Mani J, Morgenstern M, …, Warscheid B (2017) Charting organellar importomes by quantitative mass spectrometry. Nat Commun 8: 15272.

Reimann L, Wiese H, …, Warscheid B (2017) Myofibrillar Z-discs are a protein phosphorylation hot spot with PKCα modulating protein dynamics. Mol Cell Proteomics 16: 346-367.

Wrobel L, Topf U, Bragoszewski P, ..., Warscheid B*, Chacinska A* (2015) Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol. Nature 524: 485-488. *senior authorship

Weitere Aktivitäten in der wissenschaftlichen Gemeinschaft 

• Mitglied im Vorstand der European Proteomics Association (EuPA)
• Sprecher der BMBF Initiative „MSCORESYS“ (2021-2022)
• Stellvertretender Sprecher der BMBF Initiative „MSCORESYS“  (2020-2021)
• Vizepräsident der Deutschen Gesellschaft für Proteomforschung
• Editor der HUPO-PSI Quality Control Working Group
• Mitglied des Editorial Boards: Scientific Reports
• Gutachter für wissenschaftliche Fachzeitschriften: 
  Nature Nanotechnology, Nature Methods, Nature Communications, Bioinformatics, ACS nano, Journal of Proteomics, etc. 
• Fachgutachter: DFG, FWO, WWTF, ANR, NRF, DKFZ

Originalpublikationen (10 ausgewählte):

1. Navarro P, Kuharev J, Gillet LC, Bernhardt OM, MacLean B, Röst HL, Tate SA, Tsou CC, Reiter L, Distler U, Rosenberger G, Perez-Riverol Y, Nesvizhskii AI, Aebersold R, Tenzer S. 2016. A multicenter study benchmarks software tools for label-free proteome quantification. 
   Nat Biotechnol. 34(11):1130-1136. doi: 10.1038/nbt.3685.           
   Zitationen: 169
2. Distler U, Kuharev J, Navarro P, Tenzer S. 2016. Label-free quantification in ion mobility-enhanced data-independent acquisition proteomics.
   Nat Protoc. 11(4):795-812. doi: 10.1038/nprot.2016.042.            
   Zitationen: 145
3. Distler U, Kuharev J, Navarro P, Levin Y, Schild H, Tenzer S. 2014. Drift time-specific collision energies enable deep-coverage data-independent acquisition proteomics.
   Nat Methods. 11(2):167-70. doi: 10.1038/nmeth.2767.5.              
   Zitationen: 316
4. Tenzer S*, Docter D, Kuharev J, Musyanovych A, Fetz V, Hecht R, Schlenk F, Fischer D, Kiouptsi K, Reinhardt C, Landfester K, Schild H, Maskos M, Knauer SK, Stauber RH*. 2013. Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology. *corresponding authors
   Nat Nanotechnol. 8(10):772-81. doi: 10.1038/nnano.2013.181.          
   Zitationen: 1482
5. Adamopoulou E, Tenzer S, Hillen N, Klug P, Rota IA, Tietz S, Gebhardt M, Stevanovic S, Schild H, Tolosa E, Melms A, Stoeckle C. 2013. Exploring the MHC-peptide matrix of central tolerance in the human thymus.
   Nat Commun. 4:2039. doi: 10.1038/ncomms3039               
   Zitationen: 78
6. Günther C, Martini E, Wittkopf N, Amann K, Weigmann B, Neumann H, Waldner MJ, Hedrick SM, Tenzer S, Neurath MF, Becker C. 2011. Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.
   Nature. 477(7364):335-9. doi: 10.1038/nature10400.             
   Zitationen: 666
7. Tenzer S, Docter D, Rosfa S, Wlodarski A, Kuharev J, Rekik A, Knauer SK, Bantz C, Nawroth T, Bier C, Sirirattanapan J, Mann W, Treuel L, Zellner R, Maskos M, Schild H, Stauber RH. 2011. Nanoparticle Size Is a Critical Physicochemical Determinant of the Human Blood Plasma Corona: A Comprehensive Quantitative Proteomic Analysis. 
   ACS Nano. 5(9):7155-67. doi: 10.1021/nn201950e                
   Zitationen: 710
8. Tenzer S, Wee E, Burgevin A, Stewart-Jones G, Friis L, Lamberth K, Chang CH, Harndahl M, Weimershaus M, Gerstoft J, Akkad N, Klenerman P, Fugger L, Jones EY, McMichael AJ, Buus S, Schild H, van Endert P, Iversen AK. 2009. Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance.
   Nat Immunol. 10(6):636-46. doi: 10.1038/ni.1728.                 
   Zitationen: 191
9. Reineke J*, Tenzer S*, Rupnik M, Koschinski A, Hasselmayer O, Schrattenholz A, Schild H, von Eichel-Streiber C. 2007. Autocatalytic cleavage of Clostridium difficile toxin B. *contributed equally
   Nature. 446(7134):415-9.                              
   Zitationen: 248
10. Tenzer S, Peters B, Bulik S, Schoor O, Lemmel C, Schatz MM, Kloetzel PM, Rammensee HG, Schild H, Holzhütter HG. 2005. Modeling the MHC class I pathway by combining predictions of proteasomal cleavage, TAP transport and MHC class I binding. 
    Cell Mol Life Sci. 62(9):1025-37.                        
    Zitationen: 295